The chromosomes which segregate in anaphase I of meiosis are usually physically bound together through chiasmata. This association is necessary for proper segregation, since univalents sort independently from one another in the first meiotic division and this frequently leads to genetically unbalanced offspring. There are, however, a number of species where genetic exchanges in the form of meiotic cross‐overs, the prerequisite of the formation of chiasmata, are routinely missing in one sex or between specific chromosomes. These species nevertheless manage to (...) segregate these non‐exchange chromosomes. There are four direct modes for associating achiasmatic chromosomes: (a) modified SC, (b) adhesion of chromatids comparable to somatic pairing, (c) ‘stickiness’ of heterochromatin or (d) specific ‘segregation bodies’, consisting of material structurally different from chromatin. There is also the possibility that the spindlepossibly joining forces with the kinetochores‐carries out the faithful segregation of univalents which are not directly physically attached to one another. Finally, amphitelic orientation of univalents in metaphase I and pairing of the chromatids in meiosis II appear to ensure correct segregation as well. (shrink)

Affective congruency effects in the evaluation task can be explained by either spreading of activation or response competition. Eliminating effects of response compatibility by using other tasks (semantic categorisation, naming task) typically also eliminates affective congruency effects. However, there is no need for processing the affective information of the stimuli in these tasks either, which could be necessary for an affectively mediated spreading of activation (Spruyt et al., 2007, 2009, 2012). We introduced a new task to further test this hypothesis. (...) The valent/neutral-categorisation task does not confound affective congruency with response compatibility, but still requires a processing of the stimuli's valence. No affective congruency effect was obtained with this task in two experiments, disfavouring a conditional spreading activation account. On the other hand, a significant priming effect was found for associated word pairs in Experiment 1, providing evidence for the sensitivity of the task to detect spreading activation processes. (shrink)

Die von F. Rapp propagierte "starke Falsifikation" ist weder ein vertretbares noch ein in den empirischen Wissenschaften übliches Verfahren. Die gängigsten Verfahren zur Theorienmodifikation sind sogar mit der "starken Falsifikation" logisch unverträglich. Außerdem ist die "starke Falsifikation" häufig deshalb nicht anwendbar, weil wir bereits Instanzen kennen, welche die durch die "starke Falsifikation" zu erzielende Hypothese falsifizieren würden. Die "starke Falsifikation" schreibt ferner in manchen Fällen die Rückkehr zu bereits falsifizierten Hypothesen vor. Rapps Annahme, die Möglichkeit der wissenschaftlichen Prognose sei davon (...) abhängig, ob man das Verfahren der "starken Falsifikation" akzeptiert oder nicht, ist unhaltbar. (shrink)

This volume contains a selection of nine essays with an interdisciplinary perspective. They were originally presented at the Sixth International Conference on Word and Music Studies, which was held at Edinburgh University in June 2007 and was organized by the International Association for Word and Music Studies (WMA). The contributions to this volume focus on self-reference in various systematic, historical and intermedial ways. Self-reference - including, as a special case, metareference (the self-conscious reflection on music, literature and other medial concerns) (...) - is explored, among others, in instrumental music by Mozart, Mahler and Satie, in the structure and performance of (meta-)operas, in operatic adaptations of drama and filmic adaptations of opera, as well as in intermedial novelistic references to music. The essays cover a historical range from the 18th century to the present and are of interest to literary and opera scholars and students, musicologists as well as all readers generally interested in medial self-reference and intermediality studies. (shrink)

After 30 years of research, the mechanisms underlying the evaluative priming effect are still a topic of debate. In this study, we tested whether the evaluative priming effect can result from associative relatedness rather than evaluative congruency. Stimuli that share the same evaluative connotation are more likely to show some degree of non-evaluative associative relatedness than stimuli that have a different evaluative connotation. Therefore, unless associative relatedness is explicitly controlled for, evaluative priming effects reported in earlier research may be driven (...) by associative relatedness instead of evaluative relatedness. To address this possibility, we performed an evaluative priming study in which evaluative congruency and associative relatedness were manipulated independently from each other. The valent/neutral categorisation task was used to ensure evaluative stimulus processing in the absence of response priming effects. Results showed an effect of associative relatedness but no effect of evaluative congruency. Our findings highlight the importance of controlling for associative relatedness when testing for evaluative priming effects. (shrink)

Cultural and biographical influences on the expression of emotions manifest themselves in so-called “display rules.” These rules determine the time, intensity, and situations in which an emotion is expressed. To date, only a small number of empirical studies deal with this transformation of how migrants, who are faced with a new culture, may change their emotional expression. The present, cross-sectional study focuses on changes in anger expression as part of a complex acculturation process among Iranian migrants. To this end, Iranian (...) citizens in Iran, German citizens, and Iranian migrants in Germany were compared in terms of anger expression behavior and acculturation strategy was assessed among the migrants, using the Frankfurt Acculturation Scale. A questionnaire developed in a preliminary study was used to measure anger expression via subjective anger experience and anger expression within 16 hypothetical situations. Multivariate Analyses of Variance revealed that Iranians and Iranian migrants reported higher anger experience ratings than Germans and directed their anger more often inward. Further findings suggest that transformation processes may have affected Iranian migrants in terms of suppressed anger : Iranian migrants with a higher orientation toward German culture reported lower average anger-in scores. These results suggest that there was different emotional expression among Iranian migrants, depending on their acculturation. The results provide new insight into socio-cultural and individual adjustment processes. (shrink)

Peer review is a widely accepted instrument for raising the quality of science. Peer review limits the enormous unstructured influx of information and the sheer amount of dubious data, which in its absence would plunge science into chaos. In particular, peer review offers the benefit of eliminating papers that suffer from poor craftsmanship or methodological shortcomings, especially in the experimental sciences. However, we believe that peer review is not always appropriate for the evaluation of controversial hypothetical science. We argue that (...) the process of peer review can be prone to bias towards ideas that affirm the prior convictions of reviewers and against innovation and radical new ideas. Innovative hypotheses are thus highly vulnerable to being “filtered out” or made to accord with conventional wisdom by the peer review process. Consequently, having introduced peer review, the Elsevier journal Medical Hypotheses may be unable to continue its tradition as a radical journal allowing discussion of improbable or unconventional ideas. Hence we conclude by asking the publisher to consider re-introducing the system of editorial review to Medical Hypotheses. (shrink)

Emergence of the novel pathogenic coronavirus SARS‐CoV‐2 and its rapid pandemic spread presents challenges that demand immediate attention. Here, we describe the development of a semi‐quantitative high‐content microscopy‐based assay for detection of three major classes (IgG, IgA, and IgM) of SARS‐CoV‐2 specific antibodies in human samples. The possibility to detect antibodies against the entire viral proteome together with a robust semi‐automated image analysis workflow resulted in specific, sensitive and unbiased assay that complements the portfolio of SARS‐CoV‐2 serological assays. Sensitive, specific (...) and quantitative serological assays are urgently needed for a better understanding of humoral immune response against the virus as a basis for developing public health strategies to control viral spread. The procedure described here has been used for clinical studies and provides a general framework for the application of quantitative high‐throughput microscopy to rapidly develop serological assays for emerging virus infections. (shrink)

On November 21, 1994, Werner Marx passed away peacefully in the place he loved so well, his apartment in the Schloß in Bollschweil. Professor Marx was born in 1910 in Mulheim, Germany. He studied law and philosophy in Berlin, Freiburg, and Bonn before completing his state examination and doctorate in law in 1933. In the same year, he was removed from civil service and from an apprentice judgeship by the Nazis. After this, he emigrated first to Palestine and then (...) in 1938 to New York, where he took up academic studies again. After receiving an M.A. in economics, he completed the Ph.D. in philosophy, working with Kurt Reizler and Karl Löwith at the German University in Exile, later to become the New School for Social Research, and writing a dissertation on Aristotle’s ontology. During this period, he renewed his interest in Hegel and German Idealism, and also in Heidegger’s critique of the tradition and attempts to make “another beginning” in philosophy. Marx began teaching at the New School in 1949. After the appearance of his classic study, Heidegger and the Tradition, he was named successor to the Husserl-Heidegger chair in philosophy and director of Philosophical Seminar I in Freiburg, which he held from 1964 until his retirement in 1979. He also served as Director of the Husserl-Archives in Freiburg until his death. (shrink)

The book introduces a conception of discourse ethics, an intersubjectivist version of Kantian ethics. Analyzing contributions from Jürgen Habermas, Karl-Otto Apel, Wolfgang Kuhlmann, Albrecht Wellmer, Robert Alexy, Klaus Günther, Rainer Forst, Marcel Niquet and others, it reconstructs critical discussions on the justification of the principle of morality (part I) and on the various proposals on how to apply it (part II). It defends an alternative model of how discourse ethics can provide guidance under non-ideal circumstances and avoid both arbitrariness (...) and rigorism. (shrink)

In bisher einzigartiger Weise fasst dieser Band über die Grenzen der Disziplinen hinweg, aber auch Theorie und Praxis übergreifend die aktuelle Debatte zu den Emotionen in den Künsten zusammen. Die Aufsätze ermöglichen Fachleuten und interessierten Laien einen profunden Einblick in die Frage, was unter Affekt und Gefühl verstanden werden kann und wie Emotionen in den Künsten wirksam werden. Mit Beiträgen u. a. von den Architekten Peter Eisenman und Daniel Libeskind, dem Dichter und Büchner-Preisträger Thomas Kling, dem Komponisten Dieter Schnebel, den (...) Philosophinnen Agnes Heller und Brigitte Scheer, dem Psychologen Rainer Krause unddem Kunsthistoriker Werner Hofmann. Verkaufsargumente: - interdisziplinärer Sammelband, der Theorie und Praxis verbindet - bekannte Namen unter den Beiträgern, u.a. die Architekten Peter Eisenmann und Daniel Libeskind - umfassender überblick über die Debatte zu Emotionen in den Künsten, für interessierte Laien sowie für Fachleute. (shrink)

Featuring essays by some of the most prominent names in contemporary political and cultural theory, _Sovereignty in Ruins_ presents a form of critique grounded in the conviction that political thought is itself an agent of crisis. Aiming to develop a political vocabulary capable of critiquing and transforming contemporary political frameworks, the contributors advance a politics of crisis that collapses the false dichotomies between sovereignty and governmentality and between critique and crisis. Their essays address a wide range of topics, such as (...) the role history plays in the development of a politics of crisis; Arendt's controversial judgment of Adolf Eichmann; Strauss's and Badiou's readings of Plato's _Laws_; the acceptance of the unacceptable; the human and nonhuman; and flesh as a biopolitical category representative of the ongoing crisis of modernity. Altering the terms through which political action may take place, the contributors think through new notions of the political that advance countermodels of biopolitics, radical democracy, and humanity. Contributors. Judith Butler, George Edmondson, Roberto Esposito, Carlo Galli, Klaus Mladek, Alberto Moreiras, Andrew Norris, Eric L. Santner, Adam Sitze, Carsten Strathausen, Rei Terada, Cary Wolfe. (shrink)

Unterscheidung der Gegebenheiten von ihrem wahren Wesen. Eine Lehrschrift der Yogacara-Schule in tibetischer Überlieferung. Klaus-Dieter Mathes., Indica et Tibetica Verlag, Swisstal-Odendorf 1996. viii, 256 pp. pb DM64. ISBN 3 923 776 26 8.

Bringing these two emergent areas of thought into direct conversation in Before the Law, Cary Wolfe fosters a new discussion about the status of nonhuman animals and the shared plight of humans and animals under biopolitics.